\u0130nsan ve hayvanlar\u0131 hastal\u0131klardan koruma \u00e7al\u0131\u015fmalar\u0131 \u00e7ok \u00f6ncelere kadar uzanmaktad\u0131r. Bu y\u00f6ndeki ilk ad\u0131m\u0131, bir \u0130ngiliz olan, Edward Jenner (1749-1823) atm\u0131\u015ft\u0131r. Ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131n kurucusu olarak tan\u0131lan ara\u015ft\u0131r\u0131c\u0131, s\u0131\u011f\u0131r \u00e7i\u00e7e\u011fi alan bir \u015fahs\u0131n, insan \u00e7i\u00e7e\u011fine kar\u015f\u0131 ba\u011f\u0131\u015f\u0131k olaca\u011f\u0131n\u0131 ve hastalanmayaca\u011f\u0131n\u0131 g\u00f6stermi\u015f ve a\u015f\u0131lama ile immunitenin elde edilebilece\u011fi g\u00f6r\u00fc\u015f\u00fcn\u00fc yerle\u015ftirmi\u015ftir. Pasteur de ayn\u0131 tarzda, haz\u0131rlad\u0131\u011f\u0131 bir\u00e7ok a\u015f\u0131larla (tavuk koleras\u0131, koyun antraks\u0131 ve kuduza kar\u015f\u0131 yapt\u0131\u011f\u0131 a\u015f\u0131lar) ve bunlarla elde etti\u011fi ba\u011f\u0131\u015f\u0131kl\u0131k o devir i\u00e7in \u00e7ok \u00f6nemli bulu\u015flar aras\u0131ndad\u0131r. Emil Roux ve Alexander Yersen, 1888’de, difteri toksinini bulduktan sonra, Emil Von Behring de difteriye kar\u015f\u0131 antitoksin elde etmeyi ba\u015farm\u0131\u015ft\u0131r. August Von Wassermann (1886-1925), frenginin te\u015fhisinde Bordet Gengou, fenomenini uygulam\u0131\u015f ve kendi ad\u0131 ile bilinen Wassermann reaksiyonunu ortaya koymu\u015ftur. Nuttal, 1888’de, hayvanlar\u0131n kan\u0131nda B. anthracis i\u00e7in bakterisidal etkiye sahip maddelerin bulundu\u011funu saptam\u0131\u015ft\u0131r. Paul Ehrlich (1854-1916) ve Bordet ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131n humoral ve Elie Metschnikoff (1845-1916) da h\u00fccresel (fagositoz) y\u00f6nlerini a\u00e7\u0131klam\u0131\u015f ve bunlar\u0131n \u00f6nemi \u00fczerinde durmu\u015flard\u0131r. Jules Bordet (1871-1962) ve Gengou ile birlikte komplement fikzasyon reaksiyonunu bildirmi\u015flerdir. Albert Calmette (1868-1933) ve Guerin ile birlikte BCG ‘yi haz\u0131rlam\u0131\u015flard\u0131r. H. Durham ve Max Gruber, 1896’da, mikroorganizmalar\u0131n spesifik antiserumlar taraf\u0131ndan aglutine olduklar\u0131n\u0131 g\u00f6stermi\u015flerdir.<\/p>\n","protected":false},"excerpt":{"rendered":"
\u0130nsan ve hayvanlar\u0131 hastal\u0131klardan koruma \u00e7al\u0131\u015fmalar\u0131 \u00e7ok \u00f6ncelere kadar uzanmaktad\u0131r. Bu y\u00f6ndeki ilk ad\u0131m\u0131, bir \u0130ngiliz olan, Edward Jenner (1749-1823) atm\u0131\u015ft\u0131r. Ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131n kurucusu olarak tan\u0131lan ara\u015ft\u0131r\u0131c\u0131, s\u0131\u011f\u0131r \u00e7i\u00e7e\u011fi alan bir \u015fahs\u0131n, insan \u00e7i\u00e7e\u011fine kar\u015f\u0131 ba\u011f\u0131\u015f\u0131k olaca\u011f\u0131n\u0131 ve hastalanmayaca\u011f\u0131n\u0131 g\u00f6stermi\u015f ve a\u015f\u0131lama ile immunitenin elde edilebilece\u011fi g\u00f6r\u00fc\u015f\u00fcn\u00fc yerle\u015ftirmi\u015ftir. Pasteur de ayn\u0131 tarzda, haz\u0131rlad\u0131\u011f\u0131 bir\u00e7ok a\u015f\u0131larla (tavuk …<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1407,1403],"tags":[6111,6308,6309,6298,6107,6299],"class_list":["post-2527","post","type-post","status-publish","format-standard","hentry","category-fen-ve-teknoloji-odevleri","category-odevler","tag-fagositoz","tag-immunolojinin-tarihcesi","tag-koyun-antraksi","tag-kuduz","tag-pasteur","tag-tavuk-kolerasi"],"_links":{"self":[{"href":"https:\/\/www.islamidavet.com\/kutuphane\/wp-json\/wp\/v2\/posts\/2527","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.islamidavet.com\/kutuphane\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.islamidavet.com\/kutuphane\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.islamidavet.com\/kutuphane\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.islamidavet.com\/kutuphane\/wp-json\/wp\/v2\/comments?post=2527"}],"version-history":[{"count":0,"href":"https:\/\/www.islamidavet.com\/kutuphane\/wp-json\/wp\/v2\/posts\/2527\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.islamidavet.com\/kutuphane\/wp-json\/wp\/v2\/media?parent=2527"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.islamidavet.com\/kutuphane\/wp-json\/wp\/v2\/categories?post=2527"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.islamidavet.com\/kutuphane\/wp-json\/wp\/v2\/tags?post=2527"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}